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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Patchouli alcohol attenuates the cognitive deficits in a transgenic mouse model of Alzheimer’s disease via modulating neuropathology and gut microbiota through suppressing C/EBPβ/AEP pathway

Fig. 3

Effects of PA on pro-inflammatory cytokines, anti-inflammatory cytokines and BDNF in TgCRND8 mice. AE Pro-inflammatory and anti-inflammatory cytokines in the brain. A IFN-γ; B IL-1β; C IL-6; D TNF-α; E IL-4; F the protein expression of BDNF; GI pro-inflammatory and anti-inflammatory cytokines in the colon. G IL-1β; H IL-6; I IL-4. Data were expressed as the mean ± SEM (n = 5–6). ##p < 0.01 and ####p < 0.0001 compared with the WT group; *p < 0.05, **p < 0.01 and ***p < 0.001 compared with the Tg + vehicle group

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