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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Exploring the neuroprotective effects of montelukast on brain inflammation and metabolism in a rat model of quinolinic acid-induced striatal neurotoxicity

Fig. 4

Post-mortem immunofluorescence analysis of striatal neuroinflammation in nude and SD rats at 30 days post-lesion. GFAP- and Iba1-positive signals were measured in the PBS- (left panels) and QA-injected striatum (right panels) of nude (A, B) and SD rats (C, D) after treatment with VEH (top panels, black histogram bars) or 1 mg/kg of MLK (bottom panels, blue histogram bars). Mixed-effects two-way ANOVA with bootstrap: ****p < 0.0001, VEH vs MLK; ####p < 0.0001, PBS vs QA. Scale bars: 100 µm

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