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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice

Fig. 1

Paclitaxel treatment promotes infiltration of T cells into the DRG. A Flow cytometry gating strategy for T cells in female mice gated for CD45pos singlets isolated from L3–L5 DRG on day 13 after paclitaxel treatment. B Representative flow cytometry plots for CD3pos T cells (previously gated for CD45pos singlets) on day 13 in mice treated with paclitaxel or vehicle. C Paclitaxel treatment was associated with a significant increase in the influx of T cells in the DRG measured by flow cytometry (unpaired t-test, t = 3.601, p-value = 0.0036, df = 12) N = 7/group. Data are represented as mean ± SEM

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