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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice

Fig. 3

ICOSaa inhibits satellite cell gliosis in paclitaxel treated mice in the DRG. A Representative images of GS that labels satellite glial cells in the DRG, PRPH (peripherin, purple) and Dapi (blue). B GS trends towards a reduction in female animals treated with ICOSaa and calculated using MGI (one-way ANOVA, F = 6.399, p-value = 0.0128, post hoc Tukey, Vehicle vs. Ptx, p-value = 0.0159, Ptx vs. Ptx + ICOSaa, p-value = 0.0612) N = 5/group. Data are represented as mean ± SEMs. Scale bar = 50 µm

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