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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Understanding microglial responses in large animal models of traumatic brain injury: an underutilized resource for preclinical and translational research

Fig. 3

(Images adapted from Grovola et al. [104])

Microglia density proximal to hilar mossy cells changes following mild TBI. Representative images of hilar mossy cells from sham (a), 7-days post-injury (DPI) (d), and 30 DPI (g), microglial activity from sham (b), 7 DPI (e), and 30 DPI (h), and corresponding merged images (c, f, i) are shown (scale = 25 µm). Microglia density did not change significantly around mossy cells (j) but a histogram of the number of microglia per mossy cell indicates there are less microglia more frequently at 7 DPI compared to sham (l). There was a non-significant decrease in the number of microglia contacting mossy cell somata (k) and a non-significant leftward shift of the data distribution at 7 DPI and 30 DPI compared to sham (m)

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