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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis

Fig. 10

Nrf2 knockout abolished neurological function improvement mediated by combined curcumin-hUC-MSC treatment. A, B TTC-stained brain sections (A) and quantitative analysis (B) showing the decreased infarct volume with combined therapy in MCAO mice, N = 8. C The corner test was performed to assess neurological deficits from pre-MCAO to 21 d post MCAO injury, N = 12. D, E The neurological deficit score (NDS) on 1 d post MCAO (D) and 3 d post MCAO (D), N = 12. Cur curcumin, N.S. no significant difference, *P < 0.05, ***P < 0.001

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Journal of Neuroinflammation

ISSN: 1742-2094