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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Human umbilical cord-derived mesenchymal stem cell transplantation supplemented with curcumin improves the outcomes of ischemic stroke via AKT/GSK-3β/β-TrCP/Nrf2 axis

Fig. 3

Combined curcumin-hUC-MSC treatment alleviated inflammation and oxidative stress response in MCAO mice. AC The expression levels of pro-inflammatory cytokines IL-1β (A); TNF-α (B); and IL-6 (C) in the infarct region of the ipsilateral cerebral hemisphere; (DF) the expression levels of anti-inflammatory cytokines IL-4 (D); IL-10 (E); and TGFβ1 (F) in the infarct region of the ipsilateral cerebral hemisphere. GI The expression levels of markers of oxidative damage, MDA (G), SOD (H), and GPx (I) in the infarct region of the ipsilateral cerebral hemisphere with different treatments. Cur curcumin, N = 5; N.S. no significant difference, *P < 0.05, **P < 0.01, ***P < 0.001

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