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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: A short peptide exerts neuroprotective effects on cerebral ischemia–reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis

Fig. 6

NP1 reduced IL-1β and TNF-α content and improved cell survival. A NP1 reduced overexpression of IL-1β at the mRNA level after I/R injury in rats (n = 3). B NP1 reduced overexpression of TNF-α at the mRNA level after I/R injury in rats (n = 3). C NP1 reduced overexpression of IL-1β at the protein level after I/R injury in rats, with expression levels in each group shown (n = 3). D NP1 reduced overexpression of TNF-α at the protein level after I/R injury in rats, with expression levels in each group shown (n = 3). E NP1 reduced cell death caused by OGD/R in MTS cell viability assay. F NP1 reduced overexpression of IL-1β at the mRNA level after OGD/R injury in PC12 cells. G NP1 reduced overexpression of TNF-α at the mRNA level after OGD/R injury in PC12 cells. H NP1 reduced overexpression of IL-1β at the protein level after OGD/R injury in PC12 cells, with expression levels in each group shown. I NP1 reduced overexpression of TNF-α at the protein level after OGD/R injury in PC12 cells, with expression levels in each group shown. Data are presented as means ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094