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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: A short peptide exerts neuroprotective effects on cerebral ischemia–reperfusion injury by reducing inflammation via the miR-6328/IKKβ/NF-κB axis

Fig. 9

MiR-6328 negatively regulated IKKβ. A Expression of miR-6328 in control group and in PC12 cells after transfection of miR-6328 inhibitor and its corresponding negative control NCi. B Expression of miR-6328 in control group and in PC12 cells after transfection of miR-6328 mimic and its corresponding negative control NCm. C Expression of IKKβ at the mRNA level in control group and expression of IKKβ mRNA in PC12 cells after transfection of miR-6328 inhibitor, NCi, miR-6328 mimic, and NCm. D Expression of IKKβ in control group and expression of IKKβ protein in PC12 cells after transfection of miR-6328 inhibitor and its corresponding negative control NCi. E Expression of IKKβ in control group and expression of IKKβ protein in PC12 cells after transfection of miR-6328 mimic and its corresponding negative control NCm. F Dual-luciferase reporter shows that miR-6328 negatively regulated expression of IKKβ. Data are presented as means ± SEM. nsP ≥ 0.05. **P < 0.01, ***P < 0.001, ****P < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094