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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: TREM2 mediates physical exercise-promoted neural functional recovery in rats with ischemic stroke via microglia-promoted white matter repair

Fig. 1

Physical exercise (PE) promotes TREM2 up-regulation in rats after stroke. A Schematic diagrams of experimental time points and the surgical procedure. B, C PE promotes TREM2 protein expression in rats with MCAO; D–F The TREM2 mRNA level and protein expression are up-regulated in the brain of rats 35 days after MCAO. Further, PE promotes TREM2 expression in rats with MCAO. While TREM2-shRNA injections abolish the PE-promoted up-regulation of TREM2. Data were analyzed by one-way analysis of variance followed by Tukey’s post hoc test. Each dataset is expressed as mean ± SD for n = 6. **P < 0.01; ****P < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094