Fig. 2

PE improves long-term neurological functions of rats after MCAO. A Analysis of modified neurological severity scores (mNSS). Vehicle vs. PE + vehicle, *P < 0.05; **P < 0.01; PE + vehicle vs. PE + shRNA, ^#P < 0.05; ^##P < 0.01. B Latency to find the platform during the training days of the Morris water maze (MWM) test. Vehicle vs. PE + vehicle, *P < 0.05; **P < 0.01; PE + vehicle vs. PE + shRNA, ^#P < 0.05; ^##P < 0.01. C Comparisons of the proportion of time spent in the target quadrant during probe trial of MWM test. D Representative images of the swim paths of rats during probe trial. E Comparisons of the crossing times during probe trial of MWM test. F Representative images of the moving paths of rats in each group in the novel objective recognition test; Purple circle: novel objects. G Comparisons of the discrimination ratio in various groups. Two-way repeated measures ANOVA or one-way ANOVA and Bonferroni post hoc tests. Each dataset is expressed as mean ± SD for n = 7. *P < 0.05; **P < 0.01; ***P < 0.001