Fig. 4

TREM2 is essential for PE-promoted white matter integrity of rats after stroke. A Representative LFB staining images of corpus callosum and striatum of rats in different groups. B Location of brain tissues used for staining or western blotting. C Comparisons of relative optical densities in the above mentioned structure. D–G Correlations between relative values of optical densities in corpus callosum, striatum and the increased proportion of time spent in the target quadrant as well as between relative values of optical densities in corpus callosum, striatum and platform crossing times. H Representative FA and DEC maps of rats on the 28th day after MCAO in different groups, dotted line indicates outline of the lesion border. I Comparison of the ratio of FA values in ipsilateral (lesioned) side relative to those in non-lesioned contralateral hemispheres. One-way ANOVA and Bonferroni post hoc tests. Data are expressed as mean ± SD for n = 6. *P < 0.05; ***P < 0.001