Fig. 8

Expression of antivin-A/Acvr2B axis as determined by histological staining and western blotting. A Timepoint of the schematic design. B Representative images of colocalization of activin-A and Iba-1⁺ microglia in corpus callosum (× 40 objective, zoomed in 3). C Fluorescence intensities of activin-A co-localized with Iba-1⁺ microglia in each group. D Fluorescence intensities of activin-A co-localized with NG2⁺ OPCs in each group. E Representative images of colocalization of activin-A and NG2⁺ OPCs in corpus callosum (× 40 objective, zoomed in 3). F Representative images of colocalization of Acvr2B and NG2⁺ OPCs in corpus callosum (× 40 objective, zoomed in 3). G Fluorescence intensities of Acvr2B co-localized with NG2⁺ OPCs in each group. H Acvr2B/GAPDH ratio for the different groups. I Chemiluminescence images of Acvr2B and GADPH. One-way ANOVA and Bonferroni post hoc tests. Data are expressed as mean ± SD for n = 6. **P < 0.01; ****P < 0.0001