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Table 1 Participant demographic characteristics and neuropsychological score

From: Peripheral inflammation in behavioural variant frontotemporal dementia: associations with central degeneration and clinical measures

 

bvFTD (n = 39)

Control (n = 40)

p value

Age, years

62.31 ± 7.67

63.80 ± 6.16

0.34

Age at onset

60.03 ± 7.52

/

 

Disease duration (m)

25.44 ± 16.24

/

 

Sex (M/F)

16/23

15/25

0.75

Education, years

10.10 ± 3.64

11.16 ± 3.40

0.15

Cognitive status

   

 MMSE

16.77 ± 10.41

28.55 ± 0.90

 < 0.001

Dementia rating

   

 CDR® SB

8.36 ± 4.14

0

 < 0.001

 CDR® global

1.69 ± 0.73

0

 < 0.001

 CDR® plus NACC FTLD SB

10.72 ± 5.17

0

 < 0.001

 BEHAV

1.74 ± 0.75

0

 < 0.001

 LANG

0.62 ± 0.56

0

 < 0.001

Behavioural features

   

 FBI-total (z score)

24.44 ± 12.78 (0.82 ± 0.81)

/

/

 FBI apathy (z score)

17.56 ± 8.39 (0.80 ± 0.85)

/

/

 FBI disinhibition (z score)

6.88 ± 5.58 (0.67 ± 1.05)

/

/

Executive function

   

 TMT-A (z score)

117.56 ± 35.17 (0.75 ± 0.81)

/

/

 TMT-B (z score)

236.80 ± 81.01 (0.79 ± 0.81)

/

/

Linguistics

   

 BNT (z score)

17.77 ± 6.99 (− 0.56 ± 1.09)

/

/

Activities of daily living

   

 ADL (z score)

33.76 ± 13.20 (0.64 ± 1.11)

/

/

  1. bvFTD behavioural variant frontotemporal dementia, MMSE Mini-Mental State Examination, CDR® global standard 6 item CDR® global rating, CDR®SB sum of the boxes score of the 6 domains of the CDR, CDR® plus NACC FTLD-SB sum of the boxes score of the 6 domains of the CDR® plus the behaviour/comportment and language domains, BEHAV behaviour, LANG language, TMT Trail Making Test, FBI Frontal Behaviour Inventory, BNT Boston Naming Test. ADL activities of daily living scale; FBI, TMT, BNT and ADL are shown in z scores