Peripheral inflammation in behavioural variant frontotemporal dementia: associations with central degeneration and clinical measures

Table 3 Correlation analysis between plasma levels of cytokines and neuropsychological scales

Cytokines	Scale	r/rho	Uncorrected P value	FDR adjusted p value
BAFF/TNFSF13B	MMSE	− 0.3558	0.0422	0.2277
	FBI Apathy	0.5085	0.0005	0.0145
	FBI Total	0.4343	0.0116	0.0962
IL-4	Disease duration	− 0.3090	0.0802	0.3192
IL-6	TMT-A	0.3507	0.0454	0.2349
	CDR® plus NACC FTLD BEHAV	0.3288	0.0442	0.2319
IL-17A	CDR® global	0.4319	0.0121	0.0972
	CDR® plus NACC FTLD BEHAV	0.4272	0.0132	0.1037
TNF-α	CDR® SB	0.3613	0.0389	0.2277
	CDR® plus NACC FTLD BEHAV	0.4336	0.0117	0.0962
	CDR® plus NACC FTLD LANG	0.3473	0.0477	0.2403
	CDR® plus NACC FTLD SB	0.3840	0.0274	0.1808

MMSE Mini-Mental State Examination, CDR® global standard 6 item CDR® global rating, CDR®SB sum of the boxes scores of the 6 domains of the CDR, CDR® plus NACC FTLD-SB sum of the boxes scores of the 6 domains of the CDR® plus the behaviour/comportment and language domains, BEHAV behaviour, LANG language, TMT Trail Making Test, FBI Frontal Behaviour Inventory, BNT Boston Naming Test

ISSN: 1742-2094