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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Opposing effects of β-2 and β-1 adrenergic receptor signaling on neuroinflammation and dopaminergic neuron survival in α-synuclein-mediated neurotoxicity

Fig. 3

Blocking β-adrenergic receptors inhibits DSP-4-mediated dopaminergic neurons protection after hα-SYN overexpression. A Representative images of the SN showing dopaminergic neuron degeneration in the injected SN (TH, white) and B quantification of TH+ dopaminergic neurons in coronal sections of the SN 4 weeks after rAAV2–hα-SYN injection of WT mice in the different experimental conditions. Data is shown as mean values ± SEM, each dot represents one mouse, NS: not significant, *p < 0.05; **p < 0.01. One-way ANOVA followed by Tukey post hoc test. Scale bar = A 500 µm

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