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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: [18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data

Fig. 5

Axial and sagittal planes show [18F]F-DED volumes of distribution (VT) based on the 1TC2k compartment model at levels of neocortical regions, basal ganglia, hippocampus, cerebellum (all coronal) and brainstem (sagittal). The lesions of patients with autoimmune encephalitis and oligodendroglioma are indicated with white arrows. ATN indicates biomarker positivity for β-amyloid, tau and neurodegeneration in patients belonging to the AD continuum. MSA = multiple systems atrophy

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