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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1

Fig. 3

DMHCA decreases inflammation and inhibits NF-κB signalling pathway in acute RIR mice. a Representative immunofluorescence images of Iba-1 (red, labelled activation microglia) and GFAP (green, labelled activation macroglia). b–d Representative western blotting of a pro-inflammatory microglial marker (iNOS) and NF-KB pathway marker (p-P65, P65, p-IKK, and IKK) in retinas. Protein levels were normalized to GAPDH levels. e mRNA expression levels of clinical inflammation markers, iNOS, IL-6, caspase 1, and NLRP3 in retinas were measured using qRT-PCR

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Journal of Neuroinflammation

ISSN: 1742-2094