Fig. 2
From: Tregs dysfunction aggravates postoperative cognitive impairment in aged mice
Tregs transfusion changes mice cognitive function and structure of the blood–brain barrier. A Escape latency of old mice with Tregs transfusion. B Counts of crossing the target platform of old mice with Tregs transfusion. *P < 0.05 n = 6. Quantification of claudin1 (C) and claudin5 (D) in the CA3 region of the hippocampus. Representative immunofluorescence signals of claudin1 (E) and claudin5 (F). DAPI labeled the nuclei (blue), CD31 labeled endothelial cells (red), and claudin1 or claudin5 stained green. Magnification, ×200, *P < 0.05 n = 6