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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models

Fig. 10

Effect of nicotinic acid (NA) on body weight loss and exercise capacity in LPS-injected mice in the presence or absence of HCA2 in microglia. A The survival of mice during the experiment. B Changes in body weight of mice during the experiment. C, D Total distance mice traveled in the open field and time to enter the center box by open-field experiment. E Changes in the time it takes for mice to climb the pole through the pole-climbing experiment. F Changes in the time mice persisted on the fatigue apparatus through the rotarod experiment. Results are presented as mean ± SD (n = 6). *p < 0.05, **p < 0.01, ***p < 0.001 means significant difference

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