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Table 1 Gene profiling of MS4A7-s OE HMC3 cells

From: The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progression

Symbol

Gene name

Ensembl Gene ID

Fold change (vs. EV-control)

MF/BP/CC (Gene ontology)

CBS

Cystathionine beta-synthase

ENSG00000160200

2.80

Cystathionine beta-synthase activity

LRRC4B

Leucine-rich repeat containing 4B

ENSG00000131409

2.68

Signaling receptor binding

DMKN

Dermokine

ENSG00000161249

2.45

Cornified envelope assembly

SMOC1

SPARC related modular calcium binding 1

ENSG00000198732

2.39

Extracellular matrix binding, calcium ion binding

KIF5A

Kinesin family member 5A

ENSG00000155980

2.32

Cytoskeletal motor activity

SIM2

SIM bHLH transcription factor 2

ENSG00000159263

2.03

DNA-binding transcription factor activity, RNA polymerase II-specific

MYD88

MYD88 innate immune signal transduction adaptor

ENSG00000172936

1.92

Interleukin-1 receptor binding

PSG5

Pregnancy specific beta-1-glycoprotein 5

ENSG00000204941

1.80

Heterophilic cell–cell adhesion via plasma membrane cell adhesion molecules

ARMCX2

Armadillo repeat containing X-linked 2

ENSG00000184867

1.77

Integral component of membrane

TSPAN18

Tetraspanin 18

ENSG00000157570

1.55

Ion channel activity

  1. Fold induction of genes up-regulated in MS4A7-s OE HMC3 cells versus EV-control cells and MS4A7-l OE cells under normal growth conditions. Only genes with a fold change of 1.5 are presented