Fig. 5
From: The cervical lymph node contributes to peripheral inflammation related to Parkinson’s disease
Endoplasmic reticulum stress in dCLNs of A53T mice mainly existed in macrophages. A Representative fluorescence images of GRP78 in macrophages (CD11b positive), B cells (B220 positive) and T cells (CD3e positive) in dCLNs of WT and A53T mice. Scale bar, 200 μm in upper images, 20 μm in lower images. B Quantitative analysis of the intensity of GRP78 in dCLNs of WT and A53T mice. N = 9 images from 3 independent animals in WT group and N = 12 images from 4 independent animals in A53T group. C Quantitative analysis of the intensity of GRP78 in macrophages, B cells and T cells in dCLNs of WT and A53T mice. N = 5 independent animals. Values are means ± S.E.M, t test (B), two-way ANOVA test (C). ns, not significant; ***, P < 0.001; ****, P < 0.0001