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Table 1 Ultrasound neuromodulation parameters

From: Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation

Model

Burst

Probe

Olympus v302 1.0 MHz/1″F = 2.0″PTF 1,169,880

Frequency (MHz)

1.0

Pressure (kPa)

100 kPa; 350 kPa; 473 kPa

Voltage (mV)

94.7 mV; 409.3 mV; 1000 mV

Pulse duration (s)

1

Pulse repetition period (s)

6

Duty cycle

16.7%

Stimulation time

12 min or 6 min

  1. The system consists of a single element focused ultrasound transducer, a power amplifier and a function generator. The function generator produces a pulsed sinusoidal waveform. The pulse center frequency was 1.0 MHz; the pulse repetition period was 6 s; the pulse duration was 1 s. The duty cycle is the fraction of time that the ultrasound stimulus is active within each pulse repetition period, which was 16.7% in our study. The total stimulation time was 12 min or 6 min. The different ultrasound pressures were set as 0.1 MPa, 0.35 MPa, 0.473 MPa. The corresponding voltage was 94.7 mV, 409.3 mV and 1000 mV, respectively