Fig. 7

CD4⁺ and CD8⁺ rebound pregnancy modules. A, B Graphical illustration of the rebound pregnancy modules for CD4⁺ and CD8⁺ T cells, respectively. The rebound pregnancy modules were derived by overlapping the module genes from the RNA-seq and methylation module from each cell type. The module inference method DIAMOnD was used to construct the original modules for each omic and cell type separately. Nodes represent genes and the connecting edges show the protein–protein interactions. The networks were created based on the protein–protein interaction networks from STRINGdb (threshold > 950). Functional clustering of the genes was performed by KEGG pathway analysis. For illustrative purposes, each gene was assigned to only one pathway. Some genes were annotated to several similar pathways and the complete list of pathways, and their annotated genes can be found in Additional file 8: Table S7. MS multiple sclerosis