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Fig. 8 | Journal of Neuroinflammation

Fig. 8

From: SARS-CoV-2 envelope protein triggers depression-like behaviors and dysosmia via TLR2-mediated neuroinflammation in mice

Fig. 8

Intracisternal injection of E protein upregulated TLRs in the cortex, hippocampus and olfactory bulb. A qRT-PCR analysis showed that intracisternal injection of E protein upregulated TLR2, TLR3, TLR5 and TLR8 in the cortex. B qRT-PCR analysis indicated that intracisternal injection of E protein upregulated TLR2, TLR3, TLR4, TLR5, and TLR8 in the hippocampus. C qRT-PCR analysis showed that intracisternal injection of E protein upregulated TLR2, TLR7, and TLR8 in the olfactory bulb. n = 4; *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; n.s., no significance; Student’s t test

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Journal of Neuroinflammation

ISSN: 1742-2094