Fig. 9

Intracisternal injection of E protein upregulated TLR2 in the cortex, hippocampus and olfactory bulb. A Representative images of TLR2 expression in the cortex from mice receiving Vehicle or E protein injection. B Fluorescence area analysis showed that E protein significantly upregulated TLR2 expression in the cortex. C Representative images of TLR2 expression in the hippocampus (CA1, CA3 and DG regions) from mice receiving Vehicle or E protein injection. D–F Fluorescence area analysis showed that E protein significantly upregulated TLR2 expression in CA1, CA3 and DG regions of the hippocampus. G Representative images of TLR2 expression in the olfactory bulb from mice receiving Vehicle or E protein injection. H Fluorescence area analysis showed that E protein significantly upregulated TLR2 expression in the olfactory bulb. Scale bar: 50 μm. n ≥ 6 per group; **p < 0.01, ***p < 0.001, ****p < 0.0001; Student’s t test