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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Pathological hemodynamic changes and leukocyte transmigration disrupt the blood–spinal cord barrier after spinal cord injury

Fig. 2

Membrane expression of major tight junction (TJ) proteins remains unaltered during BSCB leakage. a Capillary western lane view images of junctional proteins. bh Quantification of the relative expression of the main TJ proteins 4 h post-SCI with NT and TTM. The concentration of each protein was calculated from the peak area in the data provided in Additional file 1: Fig. S2. (b) claudin-5 (cldn-5); (c) occludin (occln); (d) ZO-1; (e) tricellulin; (f) CD31; (g) ATPase; (h) vinculin. Vinculin was used as a loading control for ZO-1, and ATPase for the other proteins (n = 5 mice). Data are presented as the mean ± SEM; *P < 0.05; nested, one-way ANOVA (b-h)

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