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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: PLPP/CIN-mediated NF2 S10 dephosphorylation distinctly regulates kainate-induced seizure susceptibility and neuronal death through PAK1-NF-κB-COX-2-PTGES2 signaling pathway

Fig. 1

Effects of PLPP/CIN overexpression and its deletion on phosphorylations of NF2 and PAK1 under physiological condition. PLPP/CIN overexpression reduces NF2 S10 phosphorylation in a coupled with increased PAK1 S204 phosphorylation, which are reversed by its deletion. a Representative Western blot data of phosphorylations of NF2 and PAK1 in the whole hippocampus. b, c Quantifications of NF2 S10 and PAK1 S204 phosphorylations based on Western blot data (*p < 0.05 vs. WT animals, n = 7, respectively). d Linear regression analysis between NF2 S10 and PAK1 S204 phosphorylations

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Journal of Neuroinflammation

ISSN: 1742-2094