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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: PLPP/CIN-mediated NF2 S10 dephosphorylation distinctly regulates kainate-induced seizure susceptibility and neuronal death through PAK1-NF-κB-COX-2-PTGES2 signaling pathway

Fig. 3

Effects of PLPP/CIN ablation on phosphorylations of NF2 and PAK1 following KA injection. Two hours after KA injection, PLPP/CIN ablation increases NF2 S10 phosphorylation without affecting PAK1 S204 phosphorylation. a Representative Western blot data of phosphorylations of NF2 and PAK1 in the whole hippocampus. b, c Quantifications of NF2 S10 and PAK1 S204 phosphorylations based on Western blot data (*p < 0.05 vs. WT animals and #p < 0.05 vs. control animals with Newman-Keuls post-hoc test, n = 7, respectively)

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Journal of Neuroinflammation

ISSN: 1742-2094