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Fig. 11 | Journal of Neuroinflammation

Fig. 11

From: The involvement of NLRP3 inflammasome in CUMS-induced AD-like pathological changes and related cognitive decline in mice

Fig. 11

MCC950 reduced the phosphorylation level of tau protein. A The expression of target protein was detected by Western Blotting. B The secretion of BV2 cells activated by LPS + ATP induced the up-regulation of the phosphorylation level of tau protein in Ser396 site, and MCC950 could inhibit it. C The secretion of BV2 cells activated by LPS + ATP had no influence on the expression of total tau protein. The data were shown by mean and standard error (Mean ± SEM). (n = 3 for each group, *P < 0.05)

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