Fig. 4

MCC950 alleviated the activation of microglia induced by CUMS. A The expression of target protein was detected by Western Blotting. B There was no significant difference in GFAP expression among groups. C CUMS induced the up-regulation of Iba1 expression in hippocampus, while MCC950 and fluoxetine intervention could significantly improve. The data were shown by mean and standard error (Mean ± SEM). (n = 3 for each group, *P < 0.05, **P < 0.01)