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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: The involvement of NLRP3 inflammasome in CUMS-induced AD-like pathological changes and related cognitive decline in mice

Fig. 9

MCC950 ameliorated the activation of NLRP3 inflammasome in BV2 cells. A The expression of target protein was detected by Western Blotting. B MCC950 inhibited the up-regulation of NLRP3 induced by LPS + ATP. C MCC950 inhibited the activation of Caspase-1 p10 induced by LPS + ATP. D MCC950 alleviated the up-regulation of IL-1β induced by LPS + ATP. The data were shown by mean and standard error (Mean ± SEM). (n = 4 for each group, *P < 0.05, **P < 0.01, ***P < 0.001)

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Journal of Neuroinflammation

ISSN: 1742-2094