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Fig. 16 | Journal of Neuroinflammation

Fig. 16

From: Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

Fig. 16

Data of S100β (number of positive cells; panels A,B) and Iba-1 (immunoreactivity levels; panels C,D) immunofluorescence in the mPFC of FTD and wildtype male mice at PND90 after a chronic treatment with URB597 or vehicle, including representative microphotographs (panels A,C) for each genotype and treatment (scale bar = 50 μm). Details in the text. Data were expressed as means ± SEM and were analysed by one-way analysis of variance followed by the Bonferroni test (**p < 0.01, ***p < 0.005 versus wildtype mice treated with vehicle; #p < 0.05 versus FTD mice treated with vehicle)

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