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Fig. 17 | Journal of Neuroinflammation

Fig. 17

From: Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

Fig. 17

Data of Iba-1 immunofluorescence in the hippocampus (CA1 subfield and dentate gyrus) (panels A–C) of FTD and wildtype male mice at PND90 after a chronic treatment with URB597 or vehicle, including representative microphotographs (panel A) for each genotype and treatment (scale bar = 50 μm) in which dotted lines indicate the position of the granular layer where the neuronal cell bodies are located. Details in the text. Data were expressed as means ± SEM and were analysed by one-way analysis of variance followed by the Bonferroni test (*p < 0.05, ***p < 0.005 versus wildtype mice treated with vehicle; ##p < 0.01 versus FTD mice treated with vehicle)

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