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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Preclinical investigation in FAAH inhibition as a neuroprotective therapy for frontotemporal dementia using TDP-43 transgenic male mice

Fig. 3

Behavioural data obtained in FTD and wildtype male mice at different ages (from 4 up to 12 months of age) in the Rotarod (panel A) and Clasping behaviour (panel B) tests, as well as data of weight gain (from 45 up to 90 days of age) (panel C) and animal mortality (panel D) presented in a Kaplan–Meier plot. Details in the text. Data were expressed as means ± SEM of 8 wildtype mice and 7 FTD animals for motor parameters and weigth gain, and 11 wildtype mice and 9 FTD animals for animal survival. Data were analysed by two-way analysis of variance with repeated measures followed by the Bonferroni test (**p < 0.01, ***p < 0.005 versus the corresponding wildtype mice), except for animal survival that were assessed by Long-Rank test (or Chi-square test)

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Journal of Neuroinflammation

ISSN: 1742-2094