Fig. 2
From: IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection
IL-10 is important for promoting S. aureus craniotomy infection. IL-10 knockout (KO; n = 17) and wild type (WT; n = 15–17) mice were euthanized at the indicated time points following S. aureus craniotomy infection, whereupon bacterial burden and the percentages of monocyte, granulocytic myeloid-derived suppressor cell (G-MDSC), and neutrophil (PMN) infiltrates were quantified in the A brain along with resident microglia, B galea, and C bone flap. Results are combined from three independent experiments (mean ± SEM) and significant differences between IL-10 KO and WT mice are denoted by asterisks (*p < 0.05; ****p < 0.0001; unpaired Student’s t-test)