Table 2 Interpretation of model parameters
Group (Sham) | Captures IBI length differences in means between SHAM and HI averaged over all time points |
|---|---|
Dummy pre-post UCO (pre-time) | Captures the (vertical) shift of mean IBI values, induced by the interrupted treatment (UCO) |
Group*pre-post dummy | Captures the differential shift of mean IBI length values immediately after UCO - significant only for the HI group |
Pre-UCO time | Captures a linear increase of mean IBI length over time before UCO Note: Non-significant |
Post-UCO time | All 3 time associated parameters capture curve-linear changes of mean IBI lengths over time after UCO |
Post-UCO time (2) | |
Post-UCO time (3) | |
Residual variance | Captures within subjects variability (noise) |
Random intercept variance, pre-UCO time | Captures between subject variability at the outset |
Random slope variance, pre-UCO time | Captures between subject variability with respect to linear IBI changes over time before UCO (each animal has its own slope) |
Random slope variance, post-UCO time HI | Captures heterogeneity of between subject variability with respect to linear IBI changes over time after UCO; larger variable responsiveness for the HI group |