Figure 4From: Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways Muscarinic receptor-dependent regulation of DSM contractions. (A) Representative raw traces of detrusor contractions in response to 0.1 to 100 μM of carbachol (CCh) in wild-type (WT) and transient receptor potential vanilloid 1 knockout (TRPV1−/−) mice. (B) Concentration-dependent contractile responses of the detrusor muscle upon CCh stimulation.Back to article page