Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

Table 3 A summary of changes in glial cell markers, neurotrophins and cytokine concentrations in rat hippocampus after acute and subacute IL-1 administrations

As compared to acute and subacute IL-1 administrations with control groups, +, significantly up-regulated or increased; -, significantly down-regulated or decreased and NS, not significantly changed. GFAP, glial fibrillary acidic protein; NGF, nerve growth factor; BDNF, brain-derived neurotrophic factor; TrK, tyrosine kinase; APP, amyloid precursor protein.

ISSN: 1742-2094