From: Tracking neuroinflammation in Alzheimer’s disease: the role of positron emission tomography imaging
Process of interest | Biological target | Radiopharmaceutical | Reference |
---|---|---|---|
Microglial activation | 18-kDa translocator protein | [11C]PK11195 | [32] |
[11C]AC5216 | [33] | ||
[11C]PBR2806 | [34] | ||
[11C]DPA-713 | [35] | ||
[11C] DPA-714 | [36] | ||
[11C]MBMP | [37] | ||
[11C]DAC | [38] | ||
[11C]DAA1106 | [39] | ||
[11C]vinpocetine | [40] | ||
[18 F]PBR06 | [41] | ||
[18 F]FEAC | [42] | ||
[18 F]FEDAC | [42] | ||
[18 F]DAA1106 | [43] | ||
Reactive astrocytes | Monoamine oxidase B | [11C]-DED | [30] |
[11C]Sch225336 | [44] | ||
Phospholipase A2 activity | Metabolism of arachidonic acid | 1-[11C]-AA | [31] |
[18 F]FAA | [45] |