Table 3 Soluble and insoluble amyloid-beta levels measured by ELISA
Soluble (pg/μg protein) | Insoluble (pg/μg protein) | ||||||
|---|---|---|---|---|---|---|---|
AAV injection | Survival (months) | Aβ1-38 | Aβ1-40 | Aβ1-42 | Aβ1-38 | Aβ1-40 | Aβ1-42 |
GFP-AAV | 4 | 1.67 ± 0.77 | 2.97 ± 0.28 | 12.90 ± 2.24 | 9.04 ± 1.99 | 98.70 ± 36.77 | 903.27 ± 56.1 |
GFP-AAV | 6 | 3.16 ± 0.75 | 5.10 ± 0.44 | 25.37 ± 3.81 | 23.82 ± 2.83 | 335.53 ± 64.95 | 1634.87 ± 397.9 |
IFNγ-AAV | 4 | 3.68 ± 0.23 | 5.41 ± 0.91 | 27.17 ± 4.94 | 20.56 ± 8.48 | 295.78 ± 87.63 | 2855.26 ± 1267.9 |
IFNγ-AAV | 6 | 4.95 ± 0.51 | 6.57 ± 0.89 | 38.90 ± 7.35 | 27.10 ± 4.10 | 269.72 ± 55.2 | 2047.32 ± 436.0 |