Table 3 Associations of AD with HLA-B7 and HLA-Cw*0702 by study
From: Replication of the association of HLA-B7 with Alzheimer's disease: a role for homozygosity?
Allele | Study | Proportions of alleles | Adjusted‡ odds ratios of AD (95% CI, p) | |
|---|---|---|---|---|
Controls | AD | |||
HLA-B7 | Previous† | 10/112 | 26/110 | 3.1 (1.2–8.0, 0.02) |
Replication | 32/286 | 46/282 | 1.9 (1.03–3.4, 0.04) | |
All | 42/398 | 72/392 | 2.3 (1.4–3.7, 0.001) | |
HLA-Cw*0702 | Previous† | 14/112 | 28/108 | 2.7 (1.1–6.3, 0.03) |
Replication | 34/286 | 48/282 | 1.7 (0.95–2.9, 0.08) | |
All | 48/398 | 76/390 | 2.0 (1.3–3.1, 0.003) | |