Figure 2

Immunohistochemical detection and immunoscore classification; left column shows CD68 grey matter (A, C & E) and right column shows MHC-class II in white matter (B, D, & F); top is score 1, middle is score 2 & bottom is score 3 (see Materials & Method section). Shown are ×40 magnification microscopic fields of representative immunohistochemical stainings; all pictures are from sepsis patients, except for C. Insets show the morphological change of microglia.