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Figure 8 | Journal of Neuroinflammation

Figure 8

From: Repeated administration of the noradrenergic neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4) modulates neuroinflammation and amyloid plaque load in mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

Figure 8

Tyrosine hydroxylase histology in locus coeruleus. LC TH positive cell counts at 8 months (A) and 11 months (B) in WT and TG mice. There is a significant reduction in cells staining positive for TH in TG/DSP-4 vs TG/VEH at 11 months. *p < 0.05.

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