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Figure 6 | Journal of Neuroinflammation

Figure 6

From: Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice

Figure 6

Aggregates with α-synuclein are detected upon PGJ2 infusion. Immunostaining for α-synuclein (green) and TH-positive neurons (red) was performed four weeks after the last PGJ2 microinjection. Dopaminergic neurons in the SNpc of mice treated with 16.7 μg of PGJ2 exhibited clear aggregates (arrows) with α-synuclein. Panels with brackets depict ipsilateral (infused) and contralateral sections of the same mouse. Scale bar = 20 μm.

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