Figure 4
From: Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells
Effects of wedelolactone on TNF-α-induced IL-6 release. Cultured cells were pretreated with various concentrations of wedelolactone for 60 min, and then stimulated with 10 ng/ml TNF-α (closed circle) or vehicle (open circle) for 36 h. Each value represents the mean ± SD of triplicate independent determinations of a representative experiment carried out three times. Similar results were obtained with two additional and different cell preparations. *P < 0.05 in comparison to the value of TNF-α alone.