| Healthy Volunteers (n = 10) | ICP ≤20 mm Hg (n = 9) | ICP ≥25 mm Hg (n = 10) |
---|---|---|---|
Age range | 20-39 years | 19-51 years | 14-54 years |
Age (average) | 26.5 ± 5.5 years | 29.5 ± 12.1 years | 29.3 ± 11.2 years |
Gender | 8 male | 6 male | 9 male |
 | 2 female | 3 female | 1 female |
Race | 8 Caucasians | 8 Caucasians | 9 Caucasians |
 | 1 African-Americans | 1 African-Americans | 1 African-American |
 | 1 Asian |  |  |
Ethnicity | 5 non-hispanics | 6 non-hispanics | 6 non-hispanics |
 | 5 non-hispanics | 3 hispanics | 4 hispanics |
Apache II score | N/A | 17.6 ± 3.7 | 21.2 ± 3.5 |
ISS | N/A | 23.6 ± 5.4 | 19.8 ± 3.6 |
Therapy intensity level | Â | Â | Â |
first 24 hr | N/A | 4.0 ± 1.8 | 5.1 ± 4.1 |
72-120 hr | N/A | 3.2 ± 1.8 | 5.2 ± 4.0 |
Mortality at time of discharge | N/A | 0/9 (0%) | 2/10 (20%) |
Mechanism of injury | N/A | Â | Â |
motorcycle collision | Â | 3/9 (33%) | 3/10 (30%) |
motor vehicle accident | Â | 5/9 (55%)a | 5/10 (50%) |
fall | Â | 0/9 (0%) | 2/10 (20%)b |
assault | Â | 1/9 (11%) | 0/10 (0%) |
Initial CT results c | N/A | Â | Â |
skull fracture | Â | 5/9 (56%) | 5/10 (50%) |
subarachnoid hemorrhage | Â | 6/9 (67%) | 7/10 (70%) |
epidural hematoma | Â | 3/9 (33%) | 1/10 (10%) |
subdural hematoma | Â | 3/9 (33%) | 8/10 (80%) |
intraventricular hemorrhage | Â | 4/9 (44%) | 3/10 (33%) |
contusion | Â | 7/9 (78%) | 8/10 (80%) |
midline shift | Â | 3/9 (33%) | 3/10 (30%) |
edema | Â | 5/9 (56%) | 3/10 (30%) |
diffuse axonal injury | Â | 0/9 (0%) | 1/10 (10%) |