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Table 2 Demographic and clinical information for subjects used for Luminex analysis. Data is presented as mean ± SEM.

From: Serum IL-6: a candidate biomarker for intracranial pressure elevation following isolated traumatic brain injury

 

Healthy Volunteers (n = 10)

ICP ≤20 mm Hg

(n = 9)

ICP ≥25 mm Hg (n = 10)

Age range

20-39 years

19-51 years

14-54 years

Age (average)

26.5 ± 5.5 years

29.5 ± 12.1 years

29.3 ± 11.2 years

Gender

8 male

6 male

9 male

 

2 female

3 female

1 female

Race

8 Caucasians

8 Caucasians

9 Caucasians

 

1 African-Americans

1 African-Americans

1 African-American

 

1 Asian

  

Ethnicity

5 non-hispanics

6 non-hispanics

6 non-hispanics

 

5 non-hispanics

3 hispanics

4 hispanics

Apache II score

N/A

17.6 ± 3.7

21.2 ± 3.5

ISS

N/A

23.6 ± 5.4

19.8 ± 3.6

Therapy intensity level

   

first 24 hr

N/A

4.0 ± 1.8

5.1 ± 4.1

72-120 hr

N/A

3.2 ± 1.8

5.2 ± 4.0

Mortality at time of discharge

N/A

0/9 (0%)

2/10 (20%)

Mechanism of injury

N/A

  

motorcycle collision

 

3/9 (33%)

3/10 (30%)

motor vehicle accident

 

5/9 (55%)a

5/10 (50%)

fall

 

0/9 (0%)

2/10 (20%)b

assault

 

1/9 (11%)

0/10 (0%)

Initial CT results c

N/A

  

skull fracture

 

5/9 (56%)

5/10 (50%)

subarachnoid hemorrhage

 

6/9 (67%)

7/10 (70%)

epidural hematoma

 

3/9 (33%)

1/10 (10%)

subdural hematoma

 

3/9 (33%)

8/10 (80%)

intraventricular hemorrhage

 

4/9 (44%)

3/10 (33%)

contusion

 

7/9 (78%)

8/10 (80%)

midline shift

 

3/9 (33%)

3/10 (30%)

edema

 

5/9 (56%)

3/10 (30%)

diffuse axonal injury

 

0/9 (0%)

1/10 (10%)

  1. a, one subject was assaulted after motor vehicle accident
  2. b, one subject fell off a moving vehicle
  3. c, some patients may present with more than one pathology.