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Figure 6 | Journal of Neuroinflammation

Figure 6

From: A new Purkinje cell antibody (anti-Ca) associated with subacute cerebellar ataxia: immunological characterization

Figure 6

Subclass analysis revealed that the antibody belongs mainly to the IgG1 subclass (panel A). In addition, antibodies of the IgA subclass were detectable (panel B). In line with the presence of IgG1 antibodies, fixing of complement C3b was found (panel C; the two upper images show negative control experiments with an isotype control and without complement, respectively). Only very weak IgG3 reactivity and no IgG2, IgG4, or IgM antibodies were detectable in serum or CSF (not shown).

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Journal of Neuroinflammation

ISSN: 1742-2094