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Table 2 Absolute leukocyte counts and relative subset proportions in TBI patients and controls.

From: Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients

Parameter

  

HSD

  

NS

 
 

Control

Adm (≤ 3 h)

12 h

24 h

48 h

Adm (≤ 3 h)

12 h

24 h

48 h

Leukocytes

         

Counts1

5.7 ± 0.1

13.0 ± 0.1* †

11.3 ± 0.3*

11.4 ± 0.6*

10.4 ± 0.2*

18.1 ± 0.8*

12.3 ± 0.6*

11.5 ± 0.2*

11.4 ± 0.5*

PMNs

         

Counts

3.5 ± 0.1

10.8 ± 0.3* †

9.4 ± 0.1*

9.6 ± 0.2*

8.8 ± 0.1*

15.8 ± 0.4*

10.7 ± 0.2*

9.7 ± 0.1*

9.8 ± 0.1*

%

60.8 ± 0.6

82.4 ± 0.6*

83.5 ± 0.5*

83.5 ± 0.8*

83.9 ± 0.3*

86.5 ± 1.0*

86.3 ± 0.8*

84.1 ± 0.6*

85.4 ± 0.5*

Monocytes

         

Counts

0.29 ± 0.01

0.54 ± 0.02* †

0.59 ± 0.03*

0.52 ± 0.02*

0.50 ± 0.04*

0.74 ± 0.04*

0.63 ± 0.02*

0.57 ± 0.03*

0.61 ± 0.01*

%

5.03 ± 0.13

4.37 ± 0.14

5.06 ± 0.13

4.64 ± 0.11

5.02 ± 0.12

4.14 ± 0.11

4.30 ± 0.12

5.27 ± 0.13

5.32 ± 0.11

  1. 1Mean ± standard error mean (SEM) cell concentrations (×109/L).
  2. *P < 0.05 vs age-matched healthy controls; †P < 0.05 vs time-matched NS-treated patients by ANOVA