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Table 1 Clinical and neuroradiological characteristics of patients with neuromyelitis optica and relapsing myelitis.

From: Aquaporin-4 autoantibodies in neuromyelitis optica spectrum disorders: comparison between tissue-based and cell-based indirect immunofluorescence assays

 

NMO (n = 18)

RM (n = 15)

Female (%)

15 (83%)

15 (100%)

Mean onset age in years (range)

40.1 (18-64)

45.7 (17-70)

Mean duration of follow-up in years (range)

6.8 (2-16)

5.1 (1-12)

Mean number of AM attack (range)

3.1 (2-9)

2.7 (2-5)

Patients with LETM (%)

17 (94%)

12 (80%)

Mean number of ON attacks (range)

1.9 (1-6)

not applicable

Mean relapse rate in first 2 years in number of attack per year (range)

1.5 (0.5-4.0)

0.8 (0.3-2.0)

Mean length of MRI T2W hyperintense signal abnormalities in number of vertebral segments (range)

4.9 (1-16)

4.2 (1-10)

Patients with MRI brain lesions compatible with inflammatory demyelination (%)

10 (56%)

6 (40%)

Patients with CSF OCB (%)

3 (17%)

3 (20%)

Patients with other autoimmune disorders or autoantibodies (%)

9 (50%)

7 (47%)

Patients with poor visual outcome (%)

7 (39%)

not applicable

Mean EDSS score at latest follow-up (range)

5.9 (2.0-10)

5.4 (1.0-10)

Patients with poor neurological outcome (%)

12 (67%)

10 (67%)

Mortality

2 (11%)

2 (13%)

  1. Abbreviations: n = number of patients, NMO = neuromyelitis optica, AM = acute myelitis, RM = relapsing myelitis, LETM = longitudinally extensive transverse myelitis, MRI = magnetic resonance imaging, CSF = cerebrospinal fluid, OCB = oligoclonal bands, EDSS = Expanded Disability Status Scale.